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Purpose: Heavy smoking is strongly associated with schizophrenia. Schizophrenics are the heaviest smokers in the mental health population and have higher rates of smoking than the general population. This may be because they are self-medicating in order to alleviate the negative cognitive effects of the disorder and from typical antipsychotic drug treatment.
Objectives: Schizophrenic patients are motivated to smoke in an attempt to self-medicate for physiological reasons associated with cognition benefits and subjective reasons similar to those of non-psychiatric smokers, such as to decrease anxiolytic effects and stress, but schizophrenia patients report more pleasure from the ritual behavior of smokingthat was associated with their antipsychotic

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