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Introduction1.1 Prevalence and pathogenesis of chronic heart failureChronic heart failure (CHF), a potentially fatal stage of any cardiovascular disease not only demonstrates a steady growth in the general population, but also the significant economic costs of the health system in improving the clinical status of patients, improving their quality of life, reduce the risk of adverse clinical outcomes (Mosterd A., Hoes AW 2007 McMurry JJ, 2010). The European Guidelines for the diagnosis and treatment of CHF, determines the CHF, as the "pathophysiologic syndrome, in which the result of a disease of the cardiovascular system is reduced pumping function, which leads to an imbalance between the hemodynamic needs of the body and the heart needs" [16].CHF suffers 1.5-2% of the world's population [74]. The prevalence of CHF in the European population reaches 2.0%, in US - 2.2%, and in Russia - 6% and significantly increases with age [34, 63]. Currently, the number of patients with heart failure is increasing in all developed countries. This is due to an increase in survival in patients with cardiovascular disease, in particular, acute coronary syndrome, and thus objectively predisposed to the development of heart failure, as well as the steady trend to an increase in the population share of older age groups [79, …show more content…
Recent studies conducted in the US showed that the most common cause of heart failure is also hypertension in combination with ischemic heart disease or without it. Euro Heart Survey Study, conducted in 2001, analyzed the share etiologic CHF factors: the most common cause of this condition in Europe is coronary artery disease - 60%, valvular heart disease - 14%, dilated cardiomyopathy (DCM) - 11%, hypertension - 4 % of

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