27.11.2014Fertilization and DevelopmentDr. Archana RaniAssociate ProfessorDepartment of AnatomyKGMU UP, LucknowFertilization A complex interactionbetween the male andfemale gametes to forma zygote. Normally occurs in theampulla of uterine tubewithin 24 hours afterovulation.Fate of follicular cells after ovulation Corpus luteumCorpus luteum of menstruationCorpus luteum of pregnancy Corpus albicansImportant eventsTransport of oocyteTransport of sperms CapacitationAcrosome reactionThe eggs journey through the fallopian tubeto the uterusSteps in FertilizationPassage of sperm through the corona radiataPenetration of zona pellucidaFusion of plasma membranes of the sperm & oocyteCompletion of the second meiotic division of oocyteFormation of female pronucleusFormation of male pronucleusFusion of pronucleiFormation of a zygoteFirst week of Development(Fertilization to Implantation) Approx. 30 hrs. following fertilization, thezygote undergoes repeated mitotic divisions.This is termed as Cleavage. Resulting in a rapid increase in the number ofcells. These cells become smaller with eachcleavage division, known as blastomeres.Early DevelopmentCleavage in uterine tubeDevelopmental stages of zygoteImplantation About 6-7 daysafter fertilization,theembryoembeds itself intothe wall of theuterus.Early Development Morula & blastocyst Trop ...
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